The Indiana Department of Transportation says the right lane and shoulder on I-70 westbound in Clay County will close Sunday at the 23.6 mile marker.
Maintenance crews will be deep patching an area on the interstate and installing a drain just east of S.R. 59.
Crews plan to begin work after 11:00 PM and anticipate finishing the work by 10:00 AM on Monday.
Motorists are urged to use caution when driving through the work zone.